The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

May. 14, 2018
Applicant:

The Hong Kong University of Science and Technology, Hong Kong, CN;

Inventors:

Benzhong Tang, Hong Kong, CN;

Dan Ding, Hong Kong, CN;

Ji Qi, Hong Kong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); A61K 31/4985 (2006.01); A61K 41/00 (2020.01); A61K 49/22 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 41/0052 (2013.01); A61K 49/221 (2013.01); C07D 513/04 (2013.01);
Abstract

A theranostic agent can be used in both photoacoustic imaging (PAI) and photothermal therapy (PTT) applications. The theranostic agent can include a small molecule, organic compound with absorption in the near-infrared (NIR) interrogation window (700-900 nm). The compound can be a biocompatible organic nanoparticle (ONP). The theranostic agent can be effectively used in PAI and PAI-guided PTT applications. The theranostic agent can be administered to a patient to locate a tumor site in the patient using in vivo imaging techniques. Once the tumor site has been determined, the tumor site can be irradiated with near-infrared light to stop or inhibit the growth of the tumor. An exemplary theranostic agent is provided below


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