The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2022

Filed:

Jan. 28, 2019
Applicant:

Beijing Innocare Pharma Tech Co., Ltd., Beijing, CN;

Inventors:

Xiangyang Chen, Beijing, CN;

Yucheng Pang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/14 (2006.01); A61K 31/496 (2006.01); A61K 31/44 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); C07D 401/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/44 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C07D 215/14 (2013.01); C07D 401/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to a novel pentafluorosulfanyl-substituted amide compound that regulates or inhibits indoleamine 2,3-dioxygenase (IDO) activity, its preparation method and its application in medicine. Specifically, the present invention relates to a compound represented by general formula (I) and pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the compound or pharmaceutically acceptable salt thereof, application of the compound or pharmaceutically acceptable salt thereof for treating and/or preventing related disorders mediated by IDO, especially tumors, and a method for preparing the compound or pharmaceutically acceptable salt thereof. The present invention also relates to the preparation of the compound or pharmaceutically acceptable salt thereof or a pharmaceutical composition containing the compound or pharmaceutically acceptable salt thereof for the treatment and/or prevention of IDO-mediated related disorders, especially for use in tumor treatment. The substituents in the general formula (I) are the same as descripted in the specification.


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