The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
Apr. 23, 2018
Applicant:
The Jackson Laboratory, Bar Harbor, ME (US);
Inventors:
Simon W. M. John, Bar Harbor, ME (US);
Peter Alexander Williams, Tremont, ME (US);
Assignee:
The Jackson Laboratory, Bar Harbor, ME (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/455 (2006.01); A61K 48/00 (2006.01); A61K 31/19 (2006.01); A61K 31/4745 (2006.01); A61K 31/706 (2006.01); A61P 27/06 (2006.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/455 (2013.01); A61K 31/19 (2013.01); A61K 31/4745 (2013.01); A61K 31/706 (2013.01); A61K 38/45 (2013.01); A61K 45/06 (2013.01); A61K 48/00 (2013.01); A61K 48/005 (2013.01); A61K 48/0075 (2013.01); A61P 27/06 (2018.01); C12Y 207/07001 (2013.01); A61K 38/00 (2013.01); C12N 2750/14143 (2013.01);
Abstract
The invention relates to the use of a pharmaceutical composition containing nicotinamide (NAM) and/or pyruvate as a neuroprotective medicament or gene therapy in the treatment of neurodegenerative disorders, in particular axon degeneration of neuronal tissue in ocular-related neurodegeneration diseases including glaucoma.