The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2022
Filed:
Feb. 24, 2020
Applicant:
Chdi Foundation, Inc., New York, NY (US);
Inventors:
Celia Dominguez, Los Angeles, CA (US);
Jonathan Bard, New York, NY (US);
Matthew R. Lee, San Diego, CA (US);
Longbin Liu, Los Angeles, CA (US);
Michael Edward Prime, Swindon, GB;
Samuel Coe, Northampton, GB;
Assignee:
CHDI Foundation, Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 47/54 (2017.01); A61K 31/165 (2006.01); A61K 31/427 (2006.01);
U.S. Cl.
CPC ...
A61K 31/454 (2013.01); A61K 31/165 (2013.01); A61K 31/427 (2013.01); A61K 47/555 (2017.08);
Abstract
The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.