The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2022

Filed:

Oct. 30, 2018
Applicants:

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Horiba Abx Sas, Montpellier, FR;

Inventors:

Pierre Blandin, Coublevie, FR;

Anais Ali-Cherif, Clermont-Ferrand, FR;

Aurelien Daynes, Montpellier, FR;

Estelle Gremion, La Tour du Pin, FR;

Damien Isebe, Grabels, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/02 (2006.01); G06T 7/62 (2017.01); G06T 7/11 (2017.01); G01N 15/14 (2006.01); G03H 1/00 (2006.01); G03H 1/08 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
G01N 15/0227 (2013.01); G01N 15/1434 (2013.01); G01N 15/1463 (2013.01); G03H 1/0005 (2013.01); G03H 1/0866 (2013.01); G06T 7/11 (2017.01); G06T 7/62 (2017.01); G01N 2015/0073 (2013.01); G01N 2015/0233 (2013.01); G03H 2001/005 (2013.01); G03H 2210/55 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30024 (2013.01);
Abstract

The invention is a method for estimating a representative volume of particles of interest () immersed in a sample, the sample extending in at least one plane, referred to as the sample plane (P), the sample comprising a sphering agent, capable of modifying the shape of the particles, the method comprising the following steps: a) illuminating the sample by means of a light source (), the light source emitting an incident light wave () propagating towards the sample () along a propagation axis (Z); b) acquiring, by means of an image sensor (), an image (I) of the sample (), formed in a detection plane (P), the sample being arranged between the light source () and the image sensor (), each image being representative of a light wave () referred to as an exposure light wave, to which the image sensor () is exposed under the effect of illumination; c) using the image of the sample (I), acquired during step b), and a holographic propagation operator, to calculate a complex expression (A (x, y, z)) of the exposure light wave () in different positions relative to the detection plane; the method comprising a step of estimating the representative volume (AA) of the particles of interest () depending on the complex expressions calculated during step c).


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