The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2022

Filed:

Mar. 29, 2017
Applicant:

Fantasia Biopharma (Zhejiang) Co. Ltd., Jinhua, CN;

Inventors:

Frank XiaoFeng Qin, Sugar Land Houston, TX (US);

Fei Wu, Jiangsu, CN;

Zining Wang, Guangdong, CN;

Jingyun Ji, Guangdong, CN;

Jing Xia, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/79 (2006.01); C07H 21/04 (2006.01); C12N 15/867 (2006.01); C12N 15/65 (2006.01); C12N 15/86 (2006.01); C12Q 1/66 (2006.01);
U.S. Cl.
CPC ...
C12N 15/867 (2013.01); C12N 15/65 (2013.01); C12N 15/86 (2013.01); C12Q 1/66 (2013.01); C07H 21/04 (2013.01); C12N 2320/30 (2013.01); C12N 2740/10041 (2013.01); C12N 2740/16043 (2013.01); C12N 2799/04 (2013.01);
Abstract

Provided are a method for establishing a lentiviral vector system capable of directly reflecting type I interferon response, and applications thereof. The method for establishing the lentiviral vector system comprises: cutting aluciferase at the position of amino acid 109, removing 16 amino acids from N-terminus, and cloning the two polypeptides into a lentiviral vector to form a lentiviral BiLC expression vector; and cloning a shuttle plasmid of pEntry-IRF3 or pEntry-IRF5 or pEntry-IRF7 by homologous recombination into the lentiviral BiLC expression vector, so as to construct a lentiviral vector IRF3-BiLC or IRF5-BiLC or IRF7-BiLC capable of directly reflecting type I interferon response.


Find Patent Forward Citations

Qin, Frank. (2022). Lentiviral vector capable of directly reflecting type i interferon response, preparation method thereof, and applications thereof (U.S. Patent No. 11384366). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11384366

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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