The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2022
Filed:
Nov. 15, 2019
Applicant:
Arkgen Bioscions Co., Ltd., Daejeon, KR;
Inventors:
Heejoon Myung, Yongin-si, KR;
Yoonjung Hwang, Seongnam-si, KR;
Assignee:
ARKGEN BIOSCIONS CO., LTD, Daejeon, KR;
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61P 35/00 (2006.01); A61K 35/768 (2015.01); C07K 14/535 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 35/768 (2013.01); A61P 35/00 (2018.01); C07K 14/535 (2013.01); C12N 2795/10222 (2013.01); C12N 2795/10232 (2013.01); C12N 2795/10243 (2013.01); C12N 2795/10271 (2013.01);
Abstract
Provided is an oncolytic recombinant bacteriophage T7 expressing a cytokine in eukaryotic cells and displaying on its capsid a tumor specific homing peptide, thus inducing direct lysis of target tumor cells and immunological response to the phage leading to the effective anticancer effect. The phage naturally infecting bacteria, not human beings, provides a great advantage for gene manipulation and production for the development of anticancer agents.