The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2022
Filed:
Dec. 07, 2017
Applicant:
East Carolina University, Greenville, NC (US);
Inventors:
Daniel Stephen Wilkinson, Charlotte, NC (US);
Mark D. Mannie, Greenville, NC (US);
Assignee:
East Carolina University, Greenville, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61P 37/06 (2006.01); A61K 35/17 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0637 (2013.01); A61K 35/17 (2013.01); A61P 37/06 (2018.01); A61K 2035/122 (2013.01); A61K 2035/124 (2013.01); C12N 2501/15 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/24 (2013.01); C12N 2501/599 (2013.01); C12N 2502/1114 (2013.01);
Abstract
FOXP3regulatory T cells (Tregs) can represent powerful adoptive immunotherapies for autoimmune diseases, metabolic diseases, and other chronic inflammatory diseases. The present invention is related to the ability to maintain and expand stable Treg lines and can provide insight into FOXP3Treg physiology and can enable feasible strategies of Treg-based immunotherapy.