The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2022

Filed:

Aug. 29, 2019
Applicant:

Nibec Co., Ltd., Chungcheongbuk-do, KR;

Inventors:

Yoon Jeong Park, Seoul, KR;

Chong-Pyoung Chung, Seoul, KR;

Jue-Yeon Lee, Gyeonggi-do, KR;

Assignee:

NIBEC CO., LTD., Chungcheongbuk-do, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 38/00 (2006.01); A61P 1/16 (2006.01); A61P 1/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61P 1/00 (2018.01); A61P 1/16 (2018.01); A61K 38/00 (2013.01); C07K 2319/10 (2013.01);
Abstract

The present invention pertains to: a peptide having ATF3-binding ability and represented by any one amino acid sequence selected from the group consisting of SEQ ID NOs: 1 to 4; a fused peptide in which a cell-permeable peptide is bound to the peptide having ATF3-binding ability; and a use of the peptides for the treatment of inflammatory diseases, metabolic diseases, autoimmune diseases and/or fibrotic diseases. According to the present invention, a novel peptide having the ability to bind to ATF3, which is a protein serving as a biomarker and an important factor in the occurrence of various inflammatory diseases, metabolic diseases, autoimmune diseases and/or fibrotic diseases, is provided to thereby regulate the intracellular concentration of ATF3, and can thus be used for the treatment of inflammatory diseases, metabolic diseases, autoimmune diseases and/or fibrotic diseases. Moreover, the disease treatment effect can be enhanced by further fusing a peptide having intracellular permeability and an inflammation inhibitory function to the peptide.


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