The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2022

Filed:

May. 29, 2018
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Jan Jiricek, Emeryville, CA (US);

Isabelle K. Lerario, San Diego, CA (US);

Fang Liang, Encinitas, CA (US);

Xiaodong Liu, San Diego, CA (US);

Valentina Molteni, San Diego, CA (US);

Advait Suresh Nagle, San Diego, CA (US);

Shuyi Pearly Ng, Singapore, SG;

Maxim Ratnikov, San Diego, CA (US);

Jeffrey M. Smith, San Diego, CA (US);

Yongping Xie, San Diego, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7048 (2006.01); A61K 31/541 (2006.01); A61K 31/197 (2006.01); A61K 31/155 (2006.01); A61K 31/555 (2006.01); A61K 31/417 (2006.01); C07D 519/00 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61P 33/02 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 33/02 (2018.01); C07D 519/00 (2013.01); A61K 31/155 (2013.01); A61K 31/197 (2013.01); A61K 31/417 (2013.01); A61K 31/541 (2013.01); A61K 31/555 (2013.01); A61K 31/7048 (2013.01);
Abstract

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.


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