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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11384076 B1

PDFFull Text
Date of Patent:
Jul. 12, 2022

Filed:

Aug. 09, 2018

Synthesis, pharmacology and use of new and selective fms-like tyrosine kinase 3 (flt3) flt3 inhibitors

Applicants:

Universität Regensburg, Regensburg, DE;

Universitätsmedizin Der Johannes Gutenberg-universität Mainz, Mainz, DE;

Inventors:

Siavosh Mahboobi, Regensburg, DE;

Andreas Sellmer, Lappersdorf, DE;

Herwig Pongratz, Regensburg, DE;

Bernardette Pilsl, Wenzenbach, DE;

Oliver Krämer, Nackenheim, DE;

Thomas Kindler, Mainz, DE;

Mandy Beyer, Wiesbaden, DE;

Assignees:

UNIVERSITÄT REGENSBURG, Regensburg, DE;

UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ, Mainz, DE;

Attorney:

Saliwanchik, Lloyd & Eisenschenk

Primary Examiner:

Samira J Jean-Louis

Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61P 35/02 (2018.01);
Abstract

The present invention relates to small molecule compounds of formula (I) and their use as FLT3 inhibitors for the treatment of various diseases, such as acute myeloid leukemia (AML). The present invention further relates to methods of synthesizing the compounds and methods of treatment.

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Mahboobi, Siavosh. (2022). Synthesis, pharmacology and use of new and selective fms-like tyrosine kinase 3 (flt3) flt3 inhibitors (U.S. Patent No. 11384076). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11384076

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