The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2022
Filed:
Dec. 18, 2020
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Suzhou Vigonvita Life Sciences Co., Ltd., Jiangsu, CN;
Topharman Shanghai Co., Ltd., Shanghai, CN;
Jingshan Shen, Shanghai, CN;
Yang He, Shanghai, CN;
Zhen Wang, Shanghai, CN;
Jianfeng Li, Shanghai, CN;
Yongjian Liu, Shanghai, CN;
Jin Suo, Shanghai, CN;
Guanghui Tian, Jiangsu, CN;
Weiming Chen, Shanghai, CN;
Feipu Yang, Shanghai, CN;
Yu Wang, Shanghai, CN;
Xiangrui Jiang, Shanghai, CN;
Rongxia Zhang, Shanghai, CN;
Hualiang Jiang, Shanghai, CN;
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, Shanghai, CN;
SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., Jiangsu, CN;
TOPHARMAN SHANGHAI CO., LTD., Shanghai, CN;
Abstract
The present disclosure relates to a maleate salt of a benzothiophene compound, a crystalline form thereof, and a use thereof. Specifically, the present disclosure relates to a compound represented by formula (I-A), a crystalline form A thereof, a preparation method of a pharmaceutical composition including the same, and a use of the pharmaceutical composition in the preparation of drugs for preventing or treating diseases of the central nervous system. The compound represented by formula (I-A) and the crystalline form A thereof in the present disclosure have excellent physical and chemical properties, high oral bioavailability, excellent drugability, and are well-suited for pharmaceutical preparation, application, and preservation.