The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2022

Filed:

Oct. 06, 2017
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Jia Wang, Los Angeles, CA (US);

R. Michael Van Dam, Sherman Oaks, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 9/00 (2006.01); B01L 3/00 (2006.01); B01J 19/00 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502707 (2013.01); B01J 19/0093 (2013.01); B01L 3/502715 (2013.01); B01L 3/502784 (2013.01); B01L 7/52 (2013.01); B01J 2219/0072 (2013.01); B01J 2219/00495 (2013.01); B01J 2219/00873 (2013.01); B01J 2219/00993 (2013.01); B01L 2200/16 (2013.01); B01L 2300/12 (2013.01); B01L 2300/165 (2013.01); B01L 2300/1805 (2013.01);
Abstract

A microfluidic synthesis platform includes a microfluidic chip holder that has a computer controlled heating element and cooling element therein. A microfluidic chip is mountable in the microfluidic chip holder. The microfluidic chip is formed by a hydrophobic substrate having patterned thereon a hydrophilic reaction site and a plurality of hydrophilic channels or pathways extending outward from the hydrophilic reaction site and terminating at respective loading sites on the substrate, wherein the hydrophilic channels or pathways are tapered with an increasing width in an inward direction toward the hydrophilic reaction site. A fixture is provided for holding a plurality of non-contact reagent dispensing devices above the microfluidic chip at locations corresponding to the loading sites of the plurality of hydrophilic channels or pathways, the fixture further holding a moveable collection tube disposed above the hydrophilic reaction site of the microfluidic chip for removing droplets containing reaction products.


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