The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2022
Filed:
Sep. 13, 2018
Applicant:
Ultivue, Inc., Cambridge, MA (US);
Inventor:
Xi Chen, West Newton, MA (US);
Assignee:
ULTIVUE, INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); C07K 16/42 (2006.01); G01N 33/536 (2006.01); G01N 33/58 (2006.01); C07K 16/12 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6873 (2017.08); A61K 47/6849 (2017.08); C07K 16/12 (2013.01); C07K 16/42 (2013.01); G01N 33/536 (2013.01); G01N 33/58 (2013.01); G01N 33/6854 (2013.01); C07K 2317/30 (2013.01); C07K 2317/55 (2013.01);
Abstract
A method for exchange imaging of at least two targets in a sample includes (a) incubating a sample with at least two or more target-recognizing antibodies, each bound to a corresponding monovalent tight antibody binder-docketing moiety (MTAB-DM) reagent capable of binding monovalently to the target-recognizing antibodies, (b) applying at least two imager moieties corresponding to the MTAB-DM, either in series, in batches, or in parallel, and (d) imaging the at least two imager moieties either in series, in batches, or in parallel.