The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2022
Filed:
Jan. 12, 2018
Applicant:
Academia Sinicia, Taipei, TW;
Inventors:
Assignee:
ACADEMIA SINICA, Taipei, TW;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/39 (2006.01); A61K 47/60 (2017.01); A61K 9/00 (2006.01); A61K 47/36 (2006.01); C07K 16/44 (2006.01); A61K 9/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 9/0085 (2013.01); A61K 47/36 (2013.01); C07K 16/44 (2013.01); A61K 9/06 (2013.01);
Abstract
A drug delivery system and methods of using such for delivering a peglyated therapeutic agent to brain. The drug delivery system may comprise an antibody, which binds polyethylene glycol (PEG), wherein the antibody is embedded in a hydrogel, which may comprises one or more biodegradable polymers, up to 60% of which contain inter-chain or intra-chain covalent crosslinks. The amount of the antibody in the drug delivery system can be about 1-2 μg per μl of the hydrogel.