The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2022
Filed:
Aug. 11, 2020
Applicant:
Chemocentryx, Inc., Mountain View, CA (US);
Inventors:
Zhenhua Miao, Mountain View, CA (US);
Thomas J. Schall, Mountain View, CA (US);
Rajinder Singh, Belmont, CA (US);
Assignee:
ChemoCentryx, Inc., San Carlos, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/437 (2006.01); A61K 31/422 (2006.01); A61K 31/41 (2006.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/41 (2013.01); A61K 31/422 (2013.01); A61K 31/437 (2013.01); A61P 13/12 (2018.01);
Abstract
Provided herein are methods of treating focal segmental glomerulosclerosis, said methods include administering to a subject in need thereof a therapeutically effective amount of a CCR2 antagonist. In some embodiments, the CCR2 antagonist is used in monotherapy. In some embodiments, the CCR2 antagonist is used in combination therapy. In some embodiments, the additional therapeutic agent is a RAAS blocker and/or an endothelin receptor inhibitor. The CCR2 antagonist may have the structure of formula (I).