The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2022

Filed:

Oct. 30, 2014
Applicants:

Kyoto Prefectural Public University Corporation, Kyoto, JP;

The Doshisha, Kyoto, JP;

Senju Pharmaceutical Co., Ltd., Osaka, JP;

Inventors:

Noriko Koizumi, Kyotanabe, JP;

Naoki Okumura, Kyotanabe, JP;

Shigeru Kinoshita, Kyoto, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/4709 (2006.01); A61K 9/00 (2006.01); A61K 31/713 (2006.01); A61K 31/519 (2006.01); A61K 38/00 (2006.01); A61K 31/437 (2006.01); A61K 39/395 (2006.01); C07K 16/22 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 9/0048 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4709 (2013.01); A61K 31/519 (2013.01); A61K 31/713 (2013.01); A61K 38/00 (2013.01); A61K 39/3955 (2013.01); C07K 16/22 (2013.01);
Abstract

The present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress. Specifically, the present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress in the corneal epithelium, the drug containing a TGFβ-signal inhibitor. As a preferred TGFβ-signal inhibitor, the drug contains 4-[4-(1,3-benzodioxole-5-yl)-5-(2-pyridinyl)-1H-imidazole-2-yl]benzamide.


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