The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2022

Filed:

Jan. 07, 2019
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Dietrich Dehlinger, San Francisco, CA (US);

Ali Agah, Menlo Park, CA (US);

Tracy Helen Fung, San Francisco, CA (US);

Emrah Kostem, Menlo Park, CA (US);

Assignee:

Illumina, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 27/414 (2006.01); B01L 3/00 (2006.01); G06K 9/62 (2022.01); G01N 21/64 (2006.01); C12Q 1/6874 (2018.01); G06V 10/75 (2022.01); G01N 21/76 (2006.01); B01L 7/00 (2006.01); G16B 30/00 (2019.01);
U.S. Cl.
CPC ...
G01N 27/4145 (2013.01); B01L 3/502715 (2013.01); C12Q 1/6874 (2013.01); G01N 21/6454 (2013.01); G06K 9/6267 (2013.01); G06V 10/751 (2022.01); B01J 2219/00711 (2013.01); B01J 2219/00722 (2013.01); B01L 7/52 (2013.01); B01L 2200/147 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0893 (2013.01); G01N 21/76 (2013.01); G01N 21/763 (2013.01); G01N 2021/6432 (2013.01); G01N 2021/6441 (2013.01); G01N 2021/6471 (2013.01); G01N 2021/6478 (2013.01); G01N 2021/6482 (2013.01); G01N 2223/40 (2013.01); G01N 2223/413 (2013.01); G05B 2219/37563 (2013.01); G16B 30/00 (2019.02);
Abstract

A biosensor for base calling is provided. The biosensor comprises a sampling device, which includes a sample surface that has an array of pixel areas and a solid-state imager that has an array of sensors. Each sensor generates pixel signals in each base calling cycle. Each pixel signal represents light gathered in one base calling cycle from one or more clusters in a corresponding pixel area of the sample surface. The biosensor further comprises a signal processor configured for connection to the sampling device. The signal processor receives and processes the pixel signals from the sensors for base calling in a base calling cycle, and uses the pixel signals from fewer sensors than a number of clusters base called in the base calling cycle. The pixel signals from the fewer sensors include at least one pixel signal representing light gathered from at least two clusters in the corresponding pixel area.


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