The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Nov. 20, 2018
Applicant:
Chang Gung Memorial Hospital, Kaohsiung, Kaohsiung, TW;
Inventors:
Ying-Hsien Huang, Kaohsiung, TW;
Ho-Chang Kuo, Kaohsiung, TW;
Assignee:
Chang Gung Memorial Hospital, Kaohsiung, Kaohsiung, TW;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/6816 (2018.01); C12Q 1/6851 (2018.01); A61P 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); A61K 2039/505 (2013.01); A61P 9/00 (2018.01); C12Q 1/6816 (2013.01); C12Q 1/6851 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present invention relates to methods that use novel biomarkers for diagnosing and/or treating Kawasaki diseases. The novel biomarkers of the invention show altered cytosine methylations state of certain CpG loci in subject with Kawasaki Disease relative to subject without Kawasaki diseases. Also provided are kits comprising at least one primer or reagent specific for the altered cytosine methylation state of certain CpG loci to detect Kawasaki Disease.