The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2022

Filed:

Jan. 28, 2016
Applicant:

Hitachi High-tech Corporation, Tokyo, JP;

Inventors:

Yohei Kawaguchi, Tokyo, JP;

Tomohiro Yasuda, Tokyo, JP;

George Chalkidis, Tokyo, JP;

Takahide Yokoi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 30/00 (2019.01); C12Q 1/6869 (2018.01); C12N 15/09 (2006.01); C12Q 1/68 (2018.01); G01N 27/447 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12N 15/09 (2013.01); C12Q 1/68 (2013.01); G01N 27/44726 (2013.01); G16B 30/00 (2019.02); B01L 3/00 (2013.01); B01L 3/5027 (2013.01); C12Q 2565/125 (2013.01);
Abstract

A base sequence determination apparatus includes (1) a mobility correction unit that outputs a mobility correction signal obtained by mobility correction of a time-series signal of a wavelength spectrum corresponding to each base, (2) a deconvolution unit that executes processes for calculating a deconvoluted signal of the mobility correction signal respectively for a plurality of parameter candidates of point spread function, calculating variance of peak intervals for the calculated deconvoluted signal, specifying a parameter of the point spread function using the calculated variance, and outputting the deconvoluted signal corresponding to the point spread function having the specified parameter as an updated deconvoluted signal, (3) a peak extracting unit that extracts a peak waveform from the updated deconvoluted signal and outputs an updated peak-extracted signal, and (4) a sequence specifying unit that inputs the updated peak-extracted signal and determines a base sequence.


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