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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11377497 B1

PDFFull Text
Date of Patent:
Jul. 05, 2022

Filed:

Jan. 23, 2018

Pd-l1 binding polypeptide or composite

Applicant:

Suzhou Alphamab Co., Ltd., Jiangsu, CN;

Inventors:

Ting Xu, Suzhou, CN;

Aiwu Zhou, Shanghai, CN;

Yuhao Jin, Suzhou, CN;

Ling Wang, Suzhou, CN;

Jie Wu, Suzhou, CN;

Hongqin Hu, Suzhou, CN;

Xiaoxiao Wang, Suzhou, CN;

Assignee:

SUZHOU ALPHAMAB CO., LTD., Jiangsu, CN;

Attorney:

Troutman Pepper Hamilton Sanders LLP

Primary Examiner:

Ilia I Ouspenski

Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 15/85 (2006.01); A61K 39/395 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 39/395 (2013.01); C12N 15/85 (2013.01); G01N 33/577 (2013.01); G01N 33/6854 (2013.01); C07K 2317/565 (2013.01);
Abstract

The present invention relates to the field of medical biology, and discloses a high-resolution crystal structure of a complex of PD-L1-blocking heavy-chain single-domain antibody KN035 binding with PD-L1, and the use of the crystal structure. The invention also relates to novel PD-L1 binding polypeptides or compounds developed based on the crystal structure and uses thereof.

Find Patent Forward Citations

Xu, Ting. (2022). Pd-l1 binding polypeptide or composite (U.S. Patent No. 11377497). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11377497

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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