The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2022

Filed:

Dec. 04, 2020
Applicant:

Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);

Inventors:

Yi Feng Zheng, Wilmington, DE (US);

Tie Q. Wei, Wilmington, DE (US);

Manoj Sharma, Hockessin, DE (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); G01N 33/94 (2006.01); G01N 33/566 (2006.01); C07K 16/44 (2006.01); C07D 497/04 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 16/44 (2013.01); G01N 33/566 (2013.01); G01N 33/9493 (2013.01); C07D 497/04 (2013.01); C07K 2317/10 (2013.01); C07K 2317/54 (2013.01);
Abstract

Methods are disclosed of designing antibodies for a sandwich assay for a small molecule having a molecular weight of about 500 to about 2,000. The method comprises preparing a first antibody that binds to the small molecule, and preparing a second antibody that binds to the small molecule at a portion of the small molecule other than a portion to which the first antibody binds. The second antibody is prepared from an immunogen that comprises a predetermined portion of the small molecule. The antibodies may be employed in sandwich assays for the small molecule.


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