The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Nov. 26, 2019
President and Fellows of Harvard College, Cambridge, MA (US);
Gregory L. Verdine, Boston, MA (US);
John Hanney McGee, Somerville, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention provides peptides comprising a sequence of X-X-X-X-X-X-XPXXPXXPGXXAXXXXLXXXXXXLXXYLXXXX(SEQ ID NO: 13) wherein the amino acids X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, X, and Xare as defined herein. The present invention further provides pharmaceutical compositions comprising the peptides and methods of using the peptides for treating proliferative diseases such as cancer which are associated with Ras. Also provided are methods of screening a library of peptide dimers using a peptide dimer display technology.