The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Mar. 13, 2014
Applicant:
Modernatx, Inc., Cambridge, MA (US);
Inventors:
William Joseph Issa, Roslindale, MA (US);
John Grant Aunins, Cambridge, MA (US);
Stephane Bancel, Cambridge, MA (US);
Assignee:
ModernaTX, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 1/06 (2006.01); C08B 37/00 (2006.01); C12Q 1/6806 (2018.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C07H 1/06 (2013.01); C08B 37/0039 (2013.01); C12N 15/1006 (2013.01); C12Q 1/6806 (2013.01);
Abstract
Disclosed herein are methods for purifying RNA comprising poly A. Also disclosed herein are compositions such as surfaces and oligonucleotides for purifying RNA comprising polyA. Other embodiments are also disclosed. Commercially-available resins having polythymidine oligonucleotide ligands typically contain less than 30 thymidine (2'deoxy) residues and some commercial resin suppliers utilize a distribution of dT chain lengths, not of a discreet length.