The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Sep. 29, 2020
Applicant:
Nippon Shinyaku Co., Ltd., Kyoto, JP;
Inventor:
Fumi Higuchi, Kyoto, JP;
Assignee:
NIPPON SHINYAKU CO., LTD., Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/06 (2006.01); C07C 309/30 (2006.01); A61K 31/506 (2006.01); A61P 11/00 (2006.01); A61P 25/00 (2006.01); A61P 37/00 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); A61P 37/06 (2018.01); C07C 309/30 (2013.01); C07B 2200/13 (2013.01);
Abstract
An object of the present invention is to provide a compound with an excellent JAK1 inhibitory activity. The compound of the invention has JAK1 inhibitory activity, and thus, immunosuppressive effect, anti-inflammatory effect, anti-proliferative effect and so on, and is useful in the treatment of the diseases, for example, rheumatoid arthritis, inflammatory bowel disease, psoriasis, vasculitis, bronchial asthma, chronic obstructive pulmonary disease, eosinophilic sinusitis and nasal polyp.