The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Jun. 21, 2021
Sharan D. Ramaswamy, Miami, FL (US);
Brittany Gonzalez, Miami, FL (US);
Ariadna Herrera, Miami, FL (US);
Alexander Williams, Miami, FL (US);
Sharan D. Ramaswamy, Miami, FL (US);
Brittany Gonzalez, Miami, FL (US);
Ariadna Herrera, Miami, FL (US);
Alexander Williams, Miami, FL (US);
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES, Miami, FL (US);
Abstract
Provided are elastin-rich bioscaffolds, enhanced via stem cell pre-seeding and flow-based mechanical conditioning followed by subsequent removal of stem cells. The bioscaffolds may accelerate cardiovascular tissue regeneration and can be used in the surgical repair/reconstruction in various cardiovascular and other surgical applications including heart valves, cardiovascular grafts, and patches. The provided acellular, elastin-rich bioscaffold will pose minimal immune risk and reduced FDA regulatory hurdles as a non-living biologic product.