The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Mar. 02, 2017
The Board of Regents of the University of Texas System, Austin, TX (US);
Jinming Gao, Plano, TX (US);
Zhijian Chen, Dallas, TX (US);
Min Luo, Irving, TX (US);
Zhaohui Wang, Dallas, TX (US);
Hua Wang, Irving, TX (US);
Haocheng Cai, Dallas, TX (US);
Gang Huang, Plano, TX (US);
Yang-Xin Fu, Dallas, TX (US);
The Board of Regents of The University of Texas System, Austin, TX (US);
Abstract
In some aspects, the present disclosure provides vaccine compositions comprising an antigen and a diblock copolymer wherein the diblock copolymer is pH responsive. In some embodiments, these compositions activate the STING and/or the interferon receptor pathways. In some embodiments, the diblock copolymer hits a pKa from about 6 to about 7.5. Also provided herein are methods of treatment using these compositions to treat an infectious disease or cancer.