The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Oct. 18, 2017
The Queen's University of Belfast, Belfast, GB;
Tracy Robson, Belfast, GB;
David Grieve, Hillsborough Down, GB;
Amy Short, Magerafelt Londonderry, GB;
Adrien Kissenpfennig, Belfast, GB;
Marie Migaud, Lurgan Armagh, GB;
Rachel Bennett, Antrim, GB;
Anita Yakkundi, Belfast, GB;
Helen McCarthy, Newtonabbey, GB;
Royal College of Surgeons in Ireland, Dublin, IE;
Abstract
The inventors have determined that increasing the expression level or activity of FKBP-L polypeptide in a subject, which can be provided by expression of nucleic acids encoding FKBP-L or by providing FKBP-L polypeptides to a subject is advantageous for use in the treatment of obesity and obesity-related disorders. In particular increased expression or activity of FKBP-L polypeptide in a subject may be used to treat excessive weight gain (which can be characterised as obesity), glucose intolerance, diabetes and metabolic syndrome, which are closely linked to obesity and insulin resistance. FKBP-L can also be used as a biomarker for obesity and obesity-related disorders.