The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2022

Filed:

Oct. 04, 2017
Applicant:

Cornell University, Ithaca, NY (US);

Inventors:

David Putnam, Ithaca, NY (US);

Lawrence Bonassar, Ithaca, NY (US);

Zhexun Sun, Ithaca, NY (US);

Assignee:

CORNELL UNIVERSITY, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/785 (2006.01); A61K 31/795 (2006.01); C08F 293/00 (2006.01); A61P 19/02 (2006.01); C08F 120/06 (2006.01); C08F 220/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/785 (2013.01); A61K 31/795 (2013.01); C08F 220/286 (2020.02); C08F 293/005 (2013.01); C08F 2438/03 (2013.01);
Abstract

The invention relates to methods of lubricating biological tissue, such as joints, bone, ocular tissue, nasal tissue, tendons, tendon capsule, and vaginal tissue, by contacting the biological tissue with an effective amount of a block copolymer lubricating composition which functions at least or better than lubricin. In particular embodiments, the method is used to treat osteoarthritis. In specific embodiments, the block copolymer has an ammonium-containing polymer block and a non-ionic hydrophilic polymer block, or the copolymer has a carboxylic acid-containing polymer block and a non-acid non-ionic hydrophilic polymer block.


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