The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2022

Filed:

Oct. 01, 2018
Applicant:

Melinta Subsidiary Corp., Morristown, NJ (US);

Inventors:

Elizabeth Alexander, Maplewood, NJ (US);

Jeffrey S. Loutit, Los Altos, CA (US);

Michael N. Dudley, San Diego, CA (US);

Assignee:

MELINTA SUBSIDIARY CORP., Morristown, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/407 (2006.01); A61P 31/04 (2006.01); A61K 9/00 (2006.01); A61K 31/69 (2006.01);
U.S. Cl.
CPC ...
A61K 31/407 (2013.01); A61K 9/0019 (2013.01); A61K 31/69 (2013.01); A61P 31/04 (2018.01);
Abstract

Methods of treating bacterial infection in immunocompromised subjects and subjects with one or more underlying malignancies include administering a combination of meropenem and vaborbactam to the subject. Suitable subjects to be treated can include a subject with a history of ongoing leukemia or lymphoma, a subject that has had an organ transplant, stem cell transplant, bone marrow transplant, or splenectomy, a subject receiving immunosuppressive medications, a subject receiving bone marrow ablative chemotherapy, a subject with neutropenia and subject suffering from or having suffered from a malignancy.


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