The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Apr. 11, 2019
Applicant:

Incyte Corporation, Wilmington, DE (US);

Inventors:

Michael D. Howell, Kennett Square, PA (US);

Hao Liu, Pennington, NJ (US);

Michael A. Pratta, Mullica Hill, NJ (US);

Assignee:

Incyte Corporation, Wilmington, DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 37/06 (2006.01); A61K 31/519 (2006.01); A61K 31/573 (2006.01); A61K 45/06 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61K 31/519 (2013.01); A61K 31/573 (2013.01); A61K 45/06 (2013.01); A61P 37/06 (2018.01); G01N 2800/245 (2013.01); G01N 2800/52 (2013.01); G01N 2800/60 (2013.01);
Abstract

Biomarkers are provided that are predictive of a subject's responsiveness to a therapy comprising a JAK inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing Graft-Versus-Host Disease.


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