The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
Aug. 13, 2019
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Klaus Hallermayer, Feldafing, DE;
Monika Soukupova, Wessobrunn, DE;
Christina Porzig, Antdorf, DE;
Ulrike Kurtkaya, Graefelfing, DE;
Leopold Von Proff, Hohenspeissenberg, DE;
Sonja Fiesel, Penzberg, DE;
Marion Herrmann, Penzberg, DE;
Stefanie Kern, Munich, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
The present disclosure relates to an antibody that specifically binds a mutated NT-proBNP having i) a mutation substituting arginine at position 46 with histidine or ii) a mutation substituting glutamic acid at position 43 with aspartic acid. Moreover, the present disclosure relates to a mutated NT-proBNP or fragment thereof. Further, envisaged by the present disclosure are kits containing the antibody of the present disclosure, or the mutated NT-proBNP of the present disclosure. The present disclosure also concerns a method for diagnosing heart failure.