The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Nov. 16, 2016
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Zhenkun Lou, Rochester, MN (US);

Tongzheng Liu, Rochester, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); C12Q 1/68 (2018.01); A61P 35/00 (2006.01); A61K 31/7064 (2006.01); A61K 31/7068 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/7064 (2013.01); A61K 31/7068 (2013.01); A61P 35/00 (2018.01); C12Q 1/68 (2013.01); G01N 33/57438 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/91215 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to methods of using HEATR1 expression levels for guiding chemotherapy treatment of pancreatic cancer. In particular, measuring lower HEATR1 expression in pancreatic cancer is associated with resistance to the use of certain chemotherapy treatments such that by changing the treatment a better prognosis may be obtained for the patient. Further, lower HEATR1 expression is related to a poorer long-term prognosis of pancreatic cancer patients thus measuring an increase or maintenance/decrease during treatment may be useful for predicting treatment response.


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