The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Jan. 29, 2016
Applicant:

The Government of the United States, As Represented BY the Secretary of the Army, Fort Detrick, MD (US);

Inventors:

Mohamed Diwan M. Abdulhameed, Frederick, MD (US);

Gregory J. Tawa, Doylestown, PA (US);

Danielle L. Ippolito, Frederick, MD (US);

John A. Lewis, Greencastle, PA (US);

Sven Anders Wallqvist, Frederick, MD (US);

Jonathan D. Stallings, Frederick, MD (US);

Matthew G. Permenter, Knoxville, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); C12Q 1/68 (2018.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 1/68 (2013.01); G01N 33/5014 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/142 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/085 (2013.01); G01N 2800/56 (2013.01);
Abstract

Disclosed are methods and articles (e.g., gene arrays or antibodies) for determining the progression or regression of liver fibrosis, for the diagnosis of liver disease, and for screening compounds for hepatotoxicity and efficacy against liver fibrosis. Related therapeutic methods also are disclosed.


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