The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
Dec. 12, 2018
Applicant:
Korea Advanced Institute of Science and Technology, Daejeon, KR;
Inventors:
Assignee:
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, Daejeon, KR;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/22 (2006.01); C12P 17/18 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C12N 9/00 (2006.01); C12N 15/67 (2006.01); C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
C12P 17/182 (2013.01); C12N 9/001 (2013.01); C12N 9/0008 (2013.01); C12N 9/1085 (2013.01); C12N 9/88 (2013.01); C12N 9/90 (2013.01); C12N 9/93 (2013.01); C12N 15/67 (2013.01); C12P 13/005 (2013.01); C12Y 102/0107 (2013.01); C12Y 103/03 (2013.01); C12Y 103/03004 (2013.01); C12Y 205/01061 (2013.01); C12Y 401/01037 (2013.01); C12Y 402/01024 (2013.01); C12Y 402/01075 (2013.01); C12Y 499/01001 (2013.01); C12Y 504/03008 (2013.01); C12Y 603/05007 (2013.01);
Abstract
The present invention relates to a microorganism variant having the ability to extracellularly produce heme, and more particularly to a metabolically engineered microorganism variant having the ability to extracellularly produce heme and a method of producing heme using the same. According to the present invention, heme, an organometallic compound which is increasingly used as a health food or food supplement for the treatment of, can be extracellularly secreted and produced in high yield using the microorganism variant, but not conventional chemical synthesis or enzymatic synthesis.