The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Oct. 25, 2019
Applicant:

Genomatica, Inc., San Diego, CA (US);

Inventors:

Priti Pharkya, San Diego, CA (US);

Anthony P. Burgard, Elizabeth, PA (US);

Mark J. Burk, San Diego, CA (US);

Assignee:

Genomatica, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 5/02 (2006.01); C12N 15/52 (2006.01); C12P 3/00 (2006.01); C12P 7/40 (2006.01); C01B 3/00 (2006.01); C08F 36/06 (2006.01); C08F 36/14 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12P 5/026 (2013.01); C01B 3/00 (2013.01); C08F 36/06 (2013.01); C08F 36/14 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/0067 (2013.01); C12N 9/10 (2013.01); C12N 9/12 (2013.01); C12N 15/52 (2013.01); C12P 3/00 (2013.01); C12P 7/40 (2013.01); C12Y 101/02007 (2013.01); C12Y 101/03013 (2013.01); C12Y 102/99003 (2013.01); Y02E 50/30 (2013.01); Y02E 60/32 (2013.01);
Abstract

The invention provides non-naturally occurring microbial organisms containing butadiene or 2,4-pentadienoate pathways comprising at least one exogenous nucleic acid encoding a butadiene or 2,4-pentadienoate pathway enzyme expressed in a sufficient amount to produce butadiene or 2,4-pentadienoate. The organism can further contain a hydrogen synthesis pathway. The invention additionally provides methods of using such microbial organisms to produce butadiene or 2,4-pentadienoate by culturing a non-naturally occurring microbial organism containing butadiene or 2,4-pentadienoate pathways as described herein under conditions and for a sufficient period of time to produce butadiene or 2,4-pentadienoate. Hydrogen can be produced together with the production of butadiene or 2,4-pentadienoate.


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