The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Mar. 01, 2018
Applicant:

Basf Agricultural Solutions Seed Us Llc, Florham Park, NJ (US);

Inventors:

Marc Linka, Düsseldorf, DE;

Fabien Poree, Valbonne, FR;

Bernd Laber, Idstein, DE;

Gudrun Lange, Kelkheim, DE;

Ernst Weber, Langenfeld, DE;

Michael Strerath, Düsseldorf, DE;

Sandra Geske, Cologne, DE;

Heike Balven-Ross, Solingen, DE;

Nina Wobst, Cologne, DE;

Wayne Coco, Pulheim, DE;

Nikolaus Pawlowski, Cologne, DE;

Jan Tebbe, Cologne, DE;

Christina Thies, Dormagen, DE;

Manuel Dubald, Raleigh, NC (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 9/02 (2006.01); C12N 15/52 (2006.01); C07K 14/195 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8274 (2013.01); C07K 14/195 (2013.01); C12N 9/0069 (2013.01); C12N 15/52 (2013.01); C12Y 113/11027 (2013.01);
Abstract

In the present invention, HPPD polypeptides and plants containing them showing a full tolerance against one or more HPPD inhibitor herbicides belonging to various chemical classes are described. A set of mutant HPPD polypeptides have been designed which have either no or only a significantly reduced affinity to HPPD inhibitor herbicides and, at the same time, the rate of dissociation of the HPPD inhibitors of the mutant HPPD polypeptide is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors. In particular, isolated polynucleotides encoding mutant HPPD polypeptides conferring tolerance to HPPD inhibitor herbicides belonging to various chemical classes are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.


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