The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
May. 12, 2016
Pioneer Hi-bred International, Inc., Johnston, IA (US);
Andrew Mark Cigan, Madison, WI (US);
Giedrius Gasiunas, Vilnius, LT;
Tautvydas Karvelis, Vilnius, LT;
Virginijus Siksnys, Vilnius, LT;
Joshua K Young, Johnston, IA (US);
Abstract
Compositions and methods are provided for rapid characterization of Cas endonuclease systems and the elements comprising such systems, including, but not limiting to, rapid characterization of PAM sequences, guide RNA elements and Cas endonucleases. Type II Cas9 endonuclease systems originating fromMlc3,DSM 15814,SL4,JCM 14932,sp. SCADC,DSM 20210,NX02,DSM 16811,are described herein. The present disclosure also describes methods for genome modification of a target sequence in the genome of a cell, for gene editing, and for inserting a polynucleotide of interest into the genome of a cell.