The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
May. 25, 2018
Applicant:
Imara Inc., Cambridge, MA (US);
Inventors:
Niels Svenstrup, Charlottenlund, DK;
Jun Zhang, Tianjin, CN;
Jikui Sun, Tianjin, CN;
Yuyin Chen, Beijing, CN;
Jianshe Kong, Franklin Park, NJ (US);
Rujian Ma, Shanghai, CN;
Junhua Zhang, Chang Zhou, CN;
Liang Qin, Chang Zhou, CN;
Huanming Xiao, Beijing, CN;
Jinxu Sun, Beijing, CN;
Xiao Meng, Shanghai, CN;
Fenglai Sun, Shanghai, CN;
Jingyang Zhu, Monmouth Junction, NJ (US);
Assignee:
Imara Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract
The present invention relates a process for the synthesis of 6-((3S,4S)-4-methyl-1-(pyrimidin-2 ylmethyl)pyrrolidin-3-yl)-3-tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one, comprising use of the chiral acid (+)-O,O-Dibenzoyl-D-tartaic acid.