The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
Nov. 09, 2017
Applicant:
Dynavax Technologies Corporation, Berkeley, CA (US);
Inventors:
Albert Frederick Candia, III, San Mateo, CA (US);
Richard Thomas Beresis, San Francisco, CA (US);
Robert L. Coffman, Portola Valley, CA (US);
Assignee:
DYNAVAX TECHNOLOGIES CORPORATION, Berkeley, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 45/06 (2006.01); C07D 231/56 (2006.01); C07D 235/18 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 45/06 (2013.01); C07D 231/56 (2013.01); C07D 235/18 (2013.01); C07D 519/00 (2013.01);
Abstract
The invention relates to compounds of formula (I): or a salt or solvate thereof, wherein the variables are as described herein. Compounds of formula (I), and pharmaceutical compositions thereof, are antagonists of toll-like receptors such as TLR7, TLR8, and/or TLR9. In certain embodiments, compounds of the invention are useful for inhibiting immune response and treating diseases associated with undesirable immune response.