The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
Oct. 31, 2018
Bristol-myers Squibb Company, Princeton, NJ (US);
Joseph E. Carpenter, Bountiful, UT (US);
Jianxin Feng, Bensalem, PA (US);
Ji Jiang, West Windsor, NJ (US);
Soong-Hoon Kim, Titusville, NJ (US);
Ying Wang, New Hope, PA (US);
Gang Wu, Princeton, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention provides compounds of Formula (I), or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor (FXR), for example, as agonists. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with FXR dysregulation, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.