The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Oct. 17, 2018
Applicant:

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Rachid Baati, Strasbourg, FR;

Jagadeesh Yerri, Strasbourg, FR;

José Dias, Brétigny sur Orge, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); A61P 39/02 (2006.01); C07D 213/53 (2006.01); C07D 213/81 (2006.01); C07D 401/12 (2006.01); C07D 405/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A61P 39/02 (2018.01); C07D 213/53 (2013.01); C07D 213/81 (2013.01); C07D 401/12 (2013.01); C07D 405/06 (2013.01); C07D 519/00 (2013.01); C07B 2200/05 (2013.01);
Abstract

Disclosed is a compound of formula (II), as well as to a process for preparing the compounds of formula (II) by a chemoselective Sonogashira reaction. It also relates to a pharmaceutical composition including at least one compound of formula (II) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organophosphorous nerve agent; in the treatment of neurological diseases such as Alzheimer's disease; and/or in the treatment of cancer; and/or for use as antiviral drug.


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