The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
Jun. 24, 2020
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Karl A. Scheidt, Evanston, IL (US);
Gary E. Schiltz, Naperville, IL (US);
Matthew R. Clutter, Deerfield, IL (US);
Ada J. Kwong, Evanston, IL (US);
Assignee:
NORTHWESTERN UNIVERSITY, Evanston, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 231/56 (2006.01); C07D 405/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); C07D 231/56 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01);
Abstract
Disclosed are indazole compounds and derivatives thereof for use as modulators of the activity of mitogen-activated protein kinase 4 (MEK4). The disclosed compounds include 3-Arylindazoles which may be formulated in pharmaceutical composition for treating cell proliferative diseases and disorders associated with MEK4 activity, including cancer.