The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Mar. 20, 2017
Applicants:

United Kingdom Research and Innovation, Swindon, GB;

Imperial Innovations Limited, South Kensington, GB;

Inventors:

Nazila Kamaly, London, GB;

Tammy Louise Kalber, London, GB;

Gavin David Kenny, London, GB;

Maya Thanou, London, GB;

Andrew David Miller, London, GB;

Jimmy David Bell, London, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/18 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 49/1812 (2013.01); B82Y 5/00 (2013.01); Y10S 977/773 (2013.01);
Abstract

The present invention provides novel liposomes comprising Gd.DOTA.DSA (gadolinium (III) 2-{4,7-bis-carboxymethyl-10-[(N,N-distearylamidomethyl-N'-amido-methyl]-1,4,7,10- =tetra-azacyclododec-1-yl}-acetic acid), characterised in that the liposome further comprises a neutral, fully saturated phospholipid component (e.g. DSPC (1,2-distearoyl-sn-glycero-3-phospocholine]), which are of particular use in the preparation of magnetic resonance contrast agents for enhancing a magnetic resonance image of tumours in a mammal.


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