The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

May. 01, 2020
Applicant:

Curevac Ag, Tübingen, DE;

Inventors:

Margit Schnee, Constance, DE;

Thomas Kramps, Tübingen, DE;

Lothar Stitz, Rottenburg, DE;

Benjamin Petsch, Tübingen, DE;

Assignee:

CureVac AG, Tübingen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/205 (2006.01); A61K 39/12 (2006.01); A61K 39/42 (2006.01); A61K 48/00 (2006.01); A61K 9/00 (2006.01); C07K 14/005 (2006.01); C07K 16/10 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0075 (2013.01); A61K 9/0021 (2013.01); A61K 39/12 (2013.01); A61K 39/205 (2013.01); A61K 39/42 (2013.01); C07K 14/005 (2013.01); C07K 16/10 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/552 (2013.01); C12N 2760/20134 (2013.01);
Abstract

The present invention relates to an mRNA sequence, comprising a coding region, encoding at least one antigenic peptide or protein of Rabies virus or a fragment, variant or derivative thereof. Additionally the present invention relates to a composition comprising a plurality of mRNA sequences comprising a coding region, encoding at least one antigenic peptide or protein of Rabies virus or a fragment, variant or derivative thereof. Furthermore it also discloses the use of the mRNA sequence or the composition comprising a plurality of mRNA sequences for the preparation of a pharmaceutical composition, especially a vaccine, e.g. for use in the prophylaxis or treatment of Rabies virus infections. The present invention further describes a method of treatment or prophylaxis of rabies using the mRNA sequence.


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