The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2022
Filed:
May. 31, 2017
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
Todd Ridky, Bryn Mawr, PA (US);
Christopher Natale, Philadelphia, PA (US);
Jeffrey Winkler, Wynnewood, PA (US);
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/565 (2006.01); A61K 45/06 (2006.01); A61K 31/19 (2006.01); A61P 35/00 (2006.01); A61K 38/15 (2006.01); A61K 31/165 (2006.01); A61K 31/4045 (2006.01); A61K 31/167 (2006.01);
U.S. Cl.
CPC ...
A61K 31/565 (2013.01); A61K 31/165 (2013.01); A61K 31/167 (2013.01); A61K 31/19 (2013.01); A61K 31/4045 (2013.01); A61K 38/15 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
The present invention includes compounds, compositions and methods that are useful for preventing or treating melanoma or any other cancer in a subject, such as a GPCR-expressing cancer. In certain embodiments, the compounds comprise estrogen (including estrogen derivatives or analogues), a selective GPER agonist and/or another G-protein coupled receptor (GPCR) agonist that increases cancer cell differentiation.