The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

May. 12, 2016
Applicant:

Incept, Llc, Lexington, MA (US);

Inventors:

Peter Jarrett, Lexington, MA (US);

Rami El-Hayek, Norwood, MA (US);

Timothy S. Jarrett, Cambridge, MA (US);

Charles D. Blizzard, Westwood, MA (US);

Amarpreet S. Sawhney, Lexington, MA (US);

Assignee:

Incept, LLC, Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A01N 43/46 (2006.01); A61K 31/55 (2006.01); A61K 31/436 (2006.01); A61K 31/44 (2006.01); A61K 31/404 (2006.01); A61K 31/502 (2006.01); A61K 31/496 (2006.01); A61K 31/56 (2006.01); A61K 31/517 (2006.01); A61K 31/444 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/436 (2013.01); A61K 9/0048 (2013.01); A61K 31/404 (2013.01); A61K 31/44 (2013.01); A61K 31/444 (2013.01); A61K 31/496 (2013.01); A61K 31/502 (2013.01); A61K 31/517 (2013.01); A61K 31/56 (2013.01);
Abstract

Drug delivery involving hydrogels as used for various medical conditions, and includes hydrogels formed in an eye with extended drug release times. An embodiment of the invention is a method of delivering a therapeutic agent to a tissue comprising forming a hydrogel in situ in an eye with a therapeutic agent dispersed in the hydrogel, the agent having a low solubility in water. The agent may be essentially insoluble in water. The hydrogel may be made so that 50% to 100% w/w of the agent is released when the hydrogel is from 100% to 50% persistent, with the persistence being a measure of the dry weight of the hydrogel relative to an initial dry weight of the hydrogel.


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