The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Jan. 22, 2019
Applicants:

Nanjing Carephar Shenghui Pharmaceutical Co., Ltd., Jiangsu, CN;

Jiangsu Carephar Pharmaceutical Co., Ltd., Jiangsu, CN;

Inventors:

Yinlin Qin, Jiangsu, CN;

Mei Su, Jiangsu, CN;

Min Ji, Jiangsu, CN;

Haidong Liu, Jiangsu, CN;

Xi Zong, Jiangsu, CN;

Xianzhi Wu, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); C07D 271/08 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4245 (2013.01); C07D 271/08 (2013.01); C07D 413/12 (2013.01);
Abstract

The present invention relates to a modulator of 1,2,5-oxadiazole indoleamine-(2,3)-dioxygenase, a preparation method and use thereof, more particularly to compounds of Formula I and Formula II, an isomer thereof, a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate thereof, and their use in preparing drugs for treating cancers, neurodegenerative diseases, eye diseases, mental disorders, depression, anxiety disorders, Alzheimer's diseases and/or autoimmune diseases. Specific meanings of R substituents in Formula I and Formula II are consistent with the description of the specification.


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