The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2022

Filed:

Apr. 24, 2020
Applicant:

Shenzhen Hightide Biopharmaceutical, Ltd., Shenzhen, CN;

Inventor:

Liping Liu, Manassas, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/48 (2006.01); A61K 31/202 (2006.01); A61K 31/232 (2006.01); A61K 31/4745 (2006.01); A61K 45/06 (2006.01); A61P 3/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/48 (2013.01); A61K 31/202 (2013.01); A61K 31/232 (2013.01); A61K 31/4745 (2013.01); A61K 45/06 (2013.01); A61P 3/00 (2018.01);
Abstract

The invention provides various novel compositions of berberine in combination with pharmacologically active EPA and DHA, and related methods of their use in treating various diseases or disorders. The pharmaceutical compositions of the invention are useful in treating and/or preventing various diseases or disorders, including metabolic diseases or disorders such as dyslipidemia, hyperglycemia, hypertriglyceridemia, hyperlipidemia, diabetic dyslipidemia, diabetic hyperlipidemia, dyslipidemia in statin-intolerance patients, diabetes, diabetic complications, hypercholesterolemia, or obesity. Additionally, the pharmaceutical compositions of the invention are useful in treating and/or preventing atherosclerosis, heart diseases, neurodegenerative diseases, inflammation, cancers, as well as various liver diseases or disorders, such as fatty liver, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, cholestatic liver diseases or graft-versus-host disease of the liver. Furthermore, the pharmaceutical compositions of the invention are useful in improving liver functions in chronic viral associated liver diseases and alcohol-related liver diseases.


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