The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2022
Filed:
Aug. 14, 2020
Applicant:
Tempus Labs, Inc., Chicago, IL (US);
Inventors:
Nike T. Beaubier, Chicago, IL (US);
Joshua S K Bell, Chicago, IL (US);
Catherine Igartua, Chicago, IL (US);
Hailey B. Lefkofsky, Chicago, IL (US);
Lee F. Langer, Chicago, IL (US);
Joshua Drews, Chicago, IL (US);
Assignee:
Tempus Labs, Inc., Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 25/10 (2019.01); G16B 40/20 (2019.01); G16B 40/30 (2019.01); G16B 30/10 (2019.01); G16B 5/20 (2019.01);
U.S. Cl.
CPC ...
G16B 25/10 (2019.02); G16B 5/20 (2019.02); G16B 30/10 (2019.02); G16B 40/20 (2019.02); G16B 40/30 (2019.02);
Abstract
Disclosed herein are systems, methods, and compositions useful for determining cellular pathway disruption comprising the use of RNA expression level information. This determined level of disruption can assist in the identification of genetic variants that alter pathway activity, to correlate these variants with disease state and disease progression, and to identify those therapeutics most likely to be effective and which should be avoided.